Voyles C R, Smadja C, Shands W C, Blumgart L H
Arch Surg. 1983 Aug;118(8):986-8. doi: 10.1001/archsurg.1983.01390080088022.
We examined a case of malignant degeneration that occurred as a long-term complication of a choledochal cyst. Analysis of the literature shows the incidence of carcinoma varies with age at the initial appearance of symptoms. The child with a choledochal cyst that appears before 10 years of age carries a minimum risk (0.7%) of subsequent malignant degeneration compared with the patient in the second decade (6.8%) and older (14.3%). Data suggest that carcinoma may be readily overlooked at the time of choledochal cyst exploration. In light of the findings, an age-adjusted strategy for management should be used.
我们检查了一例作为胆总管囊肿长期并发症发生的恶性变病例。文献分析表明，癌的发生率随症状初现的年龄而变化。10岁前出现胆总管囊肿的儿童发生后续恶性变的风险最低（0.7%），而第二十年的患者（6.8%）及更大年龄者（14.3%）风险更高。数据表明，在胆总管囊肿探查时癌可能很容易被忽视。鉴于这些发现，应采用根据年龄调整的管理策略。
