Yoshikawa K, Yoshida K, Shirai Y, Sato N, Kashima Y, Coutinho D S, Koyama S, Muto T, Yamagiwa I, Iwafuchi M
Am J Gastroenterol. 1986 May;81(5):378-84.
A 27-yr-old woman with carcinoma developing in the intrapancreatic terminal choledochus 12 yr after the initial excision of giant choledochal cyst with Roux-en-Y hepaticojejunostomy is reported. Despite the generally accepted concept that the presence of bile is associated with malignancy in the remnant biliary ducts after excision of a choledochal cyst, this is the first report of a malignant growth developing in the terminal choledochus which had been free from the bile exposure long after the excision of the choledochal cyst. Long-term follow-up of the patient is advisable even after operation for primary resection of the choledochal cyst.
报告了一名27岁女性，在初次切除巨大胆总管囊肿并行Roux-en-Y肝空肠吻合术12年后，胰内段胆总管发生癌变。尽管普遍认为胆总管囊肿切除术后残留胆管内胆汁的存在与恶性肿瘤有关，但这是首例在胆总管囊肿切除术后很长时间未接触胆汁的胆总管末端发生恶性肿瘤生长的报告。即使在胆总管囊肿初次切除术后，对患者进行长期随访也是可取的。
