Yamaguchi T, Polack F M, Valenti J, Kaufman H E
Arch Ophthalmol. 1981 Dec;99(12):2151-8. doi: 10.1001/archopht.1981.03930021027009.
Anterior radial keratotomy was performed on the left eyes of 21 rabbits. Specimens were taken for electron microscopic examination at intervals during a three-month period. The corneas were acutely inflamed for three days after surgery. Some endothelial cells beneath the incisions were damaged, and distended intercellular spaces were seen. Deeper incisions seemed to produce more severe damage. With increasing time after surgery, some of the damaged endothelial cells seemed to be recovering, while others in the areas between the incisions and in the center of the cornea were degenerating. Three months after surgery, the endothelium had recovered, but some of the peripheral intercellular spaces still were distended. These findings may be the result of continuous blinking in combination with the structural weakness of the cornea, rather than a result of chronic postsurgical inflammation.
对21只兔子的左眼实施了放射状角膜切开术。在三个月的时间里定期采集样本进行电子显微镜检查。术后角膜急性炎症持续了三天。切口下方的一些内皮细胞受损，可见细胞间隙增宽。较深的切口似乎造成了更严重的损伤。随着术后时间的增加，一些受损的内皮细胞似乎在恢复，而切口之间区域和角膜中央的其他内皮细胞则在退化。术后三个月，内皮已经恢复，但一些周边细胞间隙仍然增宽。这些发现可能是持续眨眼与角膜结构薄弱共同作用的结果，而非术后慢性炎症所致。
