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伦敦交通局巴士车库和奇西克工厂维修工人的流行病学调查。

Epidemiological survey of maintenance workers in London Transport Executive bus garages and Chiswick Works.

作者信息

Rushton L, Alderson M R, Nagarajah C R

出版信息

Br J Ind Med. 1983 Aug;40(3):340-5. doi: 10.1136/oem.40.3.340.

Abstract

A mortality study of maintenance men employed for at least one year between 1 January 1967 and 31 December 1975 at 71 London Transport bus garages and Chiswick Works has been carried out. Over 97% of the population were successfully traced to determine their vital status at 31 December 1975. The mortality observed in the study population was compared with that which would be expected from the mortality rates for the all male population of England and Wales. The mortality of the study population from all causes was much lower than expected on this basis, as was the mortality from cerebrovascular disease, ischaemic heart disease, and bronchitis. Mortality from all neoplasms was slightly less than expected overall and especially in the younger age groups. The observed deaths from cancer of the lung were approximately the same as those expected on the basis of national rates. Nevertheless, a deficit of observed deaths from lung cancer was obtained after adjusting for the higher mortality from this disease in Greater London. Raised mortality was found in subgroups of the population for several malignant disease groups but these were almost all based on small numbers of deaths, making it difficult to exclude chance effects. Both the number of men and deaths in the study were limited and the follow up time was also short. Considerable extension of the study to include more men and increase the follow up time would be required for any definite mortality patterns to emerge.

摘要

对1967年1月1日至1975年12月31日期间在伦敦交通公司的71个公交修理厂和奇西克工厂受雇至少一年的维修工人进行了一项死亡率研究。超过97%的研究对象被成功追踪,以确定他们在1975年12月31日的生命状态。将研究人群中观察到的死亡率与根据英格兰和威尔士所有男性人口死亡率预期的死亡率进行了比较。基于此,研究人群中所有原因导致的死亡率远低于预期,脑血管疾病、缺血性心脏病和支气管炎导致的死亡率也是如此。所有肿瘤导致的死亡率总体上略低于预期,尤其是在较年轻的年龄组中。观察到的肺癌死亡人数与根据全国死亡率预期的人数大致相同。然而,在对大伦敦地区该疾病较高的死亡率进行调整后,发现肺癌观察到的死亡人数存在不足。在该人群的几个恶性疾病亚组中发现死亡率升高,但这些几乎都基于少量死亡病例,因此难以排除偶然因素的影响。该研究中的男性人数和死亡人数都有限,随访时间也很短。若要出现任何明确的死亡率模式,需要大幅扩展该研究,纳入更多男性并延长随访时间。

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