作为潜在抗心律失常药物的3-二烷基氨基丙基-2-硫代乙内酰脲衍生物的合成。
Synthesis of 3-dialkylaminopropyl-2-thiohydant derivatives as potential antiarrhythmic agents.
作者信息
Ryczek J, Kusowska J
出版信息
Farmaco Sci. 1983 Jun;38(6):383-90.
PMID:6873272
Abstract
A series of 3-dialkylaminopropyl-5-monosubstituted-2-thiohydantoins were synthesized as potential antiarrhythmic agents; their pharmacological activity is comparable to that of quinidine, but weaker than that of phenytoin.
摘要
合成了一系列3-二烷基氨基丙基-5-单取代-2-硫代乙内酰脲作为潜在的抗心律失常药物；它们的药理活性与奎尼丁相当，但比苯妥英钠弱。
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