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Pharmacological properties of 3-aminoalkyl and amide derivatives of 5,5-diphenylhydantoin.

作者信息

Kieć-Kononowicz K, Stypuła E, Krupińska J, Cebo B

出版信息

Pol J Pharmacol Pharm. 1985 Sep-Oct;37(5):693-9.

PMID:3832013
Abstract

5,5-Diphenylhydantoin derivatives containing at the position 3 aminoalkyl (1, 2, 4, 5), aminohydroxyalkyl (3) and amide (6, 8) groups were synthesized. The compounds, given in a dose of 50 mg/kg, did not affect cardiac bioelectric activity and, in contrast to diphenylhydantoin, did not possess the antiarrhythmic properties and did not protect against pentetrazol seizures.

摘要

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