Garrett P G, Simpson W J
Int J Radiat Oncol Biol Phys. 1983 Aug;9(8):1121-4. doi: 10.1016/0360-3016(83)90169-4.
Between 1958 and 1980, 102 patients with the diagnosis of ependymoma were seen at the Princess Margaret Hospital. Eleven patients had recurrent disease or were treated elsewhere and 91 patients received radiation therapy following their primary surgical procedure. Fifty patients had cranial tumors and 41 had spinal tumors. The overall survival at five years was 60% and at 10 years was 54%. Those patients with spinal tumours did significantly better with a five year survival of 83% versus 43% for the group with cranial tumors. The other prognostic factors included tumor grade, functional status, age of the patient and interval from surgery to radiation. The most common site of relapse was at the original tumor location, but five patients did show spread through the craniospinal axis. An analysis of dose and the volume treated is made and recommendations for therapy given.
1958年至1980年间，玛格丽特公主医院共收治了102例诊断为室管膜瘤的患者。11例患者患有复发性疾病或在其他地方接受治疗，91例患者在初次手术后接受了放射治疗。50例患者患有颅内肿瘤，41例患有脊柱肿瘤。五年总生存率为60%，十年总生存率为54%。脊柱肿瘤患者的情况明显更好，五年生存率为83%，而颅内肿瘤患者组为43%。其他预后因素包括肿瘤分级、功能状态、患者年龄以及手术至放疗的间隔时间。最常见的复发部位是原肿瘤位置，但有5例患者确实出现了经颅脊髓轴扩散。对治疗剂量和治疗体积进行了分析，并给出了治疗建议。
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