游离和结合多巴胺在人尾状核、下丘脑及肾脏中的分布。
Distribution of free and conjugated dopamine in human caudate nucleus, hypothalamus, and kidney.
作者信息
Elchisak M A
出版信息
J Neurochem. 1983 Sep;41(3):893-6. doi: 10.1111/j.1471-4159.1983.tb04825.x.
Abstract
The occurrence of free and conjugated dopamine was determined by HPLC in human caudate nucleus, hypothalamus, and kidney. Free norepinephrine and dihydroxyphenylacetic acid levels in some tissues were also determined. Conjugated dopamine was found to account for 25% of the total DA in the kidney. Conjugated DA accounted for 2.9% and 5.1% of the total DA in the caudate nucleus and hypothalamus, respectively. These results indicate that conjugated dopamine is not homogenously distributed in human tissue.
摘要
采用高效液相色谱法测定人尾状核、下丘脑和肾脏中游离多巴胺和结合多巴胺的含量。同时也测定了一些组织中游离去甲肾上腺素和二羟基苯乙酸的水平。结果发现，结合多巴胺在肾脏中占总多巴胺的25%。在尾状核和下丘脑中，结合多巴胺分别占总多巴胺的2.9%和5.1%。这些结果表明，结合多巴胺在人体组织中的分布并不均匀。
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