朗格汉斯细胞与麻风病。
Langerhans cell and leprosy.
作者信息
Mathur N K, Mangal H N, Mathur D, Bedwal R S, Mathur R S
出版信息
Lepr India. 1983 Jan;55(1):22-8.
Langerhans cell population was counted in 44 patients of different types of leprosy and compared with 12 normal volunteers. Significant reduction in LC count was observed in cases of LL (253.44 +/- 136.83/mm2) and BL (349.36 +/- 121.67/mm2). Whereas in TT (854.60 +/- 332.01/mm2) and BT (715.76 +/- 235.33/mm2) there was no significant difference, as compared to Normal (927.43 +/- 103.87/mm2). Treatment had no influence on LC population in both the polar types of leprosy. Role of these immunocompetent dendritic cells in the pathogenesis of leprosy is discussed.
对44例不同类型麻风病患者的朗格汉斯细胞数量进行了计数，并与12名正常志愿者进行了比较。在瘤型麻风（LL，253.44 +/- 136.83/mm²）和界线类偏瘤型麻风（BL，349.36 +/- 121.67/mm²）病例中观察到朗格汉斯细胞数量显著减少。而在结核样型麻风（TT，854.60 +/- 332.01/mm²）和界线类偏结核样型麻风（BT，715.76 +/- 235.33/mm²）中，与正常组（927.43 +/- 103.87/mm²）相比无显著差异。治疗对两型麻风病的朗格汉斯细胞数量均无影响。文中讨论了这些具有免疫活性的树突状细胞在麻风病发病机制中的作用。
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