Bigelow B, Vekshtein V, Demopoulos R I
Obstet Gynecol. 1983 Sep;62(3):363-6.
The spread of endometrial carcinoma to the cervix was studied in 19 hysterectomy specimens from patients with stage II disease. None received preoperative irradiation. The tumor was found to spread in continuity from corpus to endocervix, where it involved only the surface in five patients, the surface and underlying stroma in 13, and only stroma in one case. Surface only involvement tended to correlate with a lower grade of tumor, less myometrial invasion, and a better prognosis than was associated with endocervical stromal invasion. Review of preoperative endocervical curettings, in the ten patients who underwent this fractional procedure, revealed tumor in all specimens. The authors were unable, however, to distinguish stromal involvement from surface only involvement by study of these curettings.
对19例II期子宫内膜癌患者的子宫切除标本进行了研究，以探讨子宫内膜癌向宫颈的扩散情况。所有患者均未接受术前放疗。发现肿瘤从宫体连续蔓延至宫颈管内膜，其中5例仅累及表面，13例累及表面及下方间质，1例仅累及间质。仅累及表面的情况往往与较低的肿瘤分级、较少的肌层浸润以及比宫颈管间质浸润更好的预后相关。对10例行分段诊刮术患者的术前宫颈管刮出物进行复查，发现所有标本中均有肿瘤。然而，通过对这些刮出物的研究，作者无法区分间质受累和仅表面受累情况。
