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交叉神经支配导致的同侧和对侧纤维转变。对称性原则。

Ipsi- and contralateral fibre transformations by cross-reinnervation. A principle of symmetry.

作者信息

Reichmann H, Srihari T, Pette D

出版信息

Pflugers Arch. 1983 May;397(3):202-8. doi: 10.1007/BF00584358.

DOI:10.1007/BF00584358
PMID:6878008
Abstract

Cross-reinnervation of rabbit soleus muscle by the peroneal nerve induces a 90% transformation of slow into fast fibres. These changes are reflected in corresponding transformations of the enzyme activity pattern of energy metabolism, the isozyme pattern of lactate dehydrogenase and, in confirmation of previous results (Srihari et al. 1981), transitions from a slow to a fast type myosin light chain pattern. The transformation process appears to be complete after 6 months. Similar changes, although less extensive are also found in the soleus muscle of the contralateral leg. Fibre type transitions in the contralateral muscle are not accompanied by fibre type grouping, as seen in the cross-reinnervated muscle and therefore these changes appear to result from a transformation of the motor units themselves. This phenomenon is interpreted as a compensatory process in maintaining symmetry within the neuromotor system.

摘要

腓总神经对兔比目鱼肌的交叉神经支配可使慢肌纤维90%转变为快肌纤维。这些变化反映在能量代谢酶活性模式、乳酸脱氢酶同工酶模式的相应转变上,并且正如之前的研究结果(Srihari等人,1981年)所证实的,肌球蛋白轻链模式也从慢型转变为快型。6个月后,转变过程似乎完成。对侧腿的比目鱼肌也发现了类似的变化,尽管程度较轻。对侧肌肉中的纤维类型转变并不伴有纤维类型分组现象,这与交叉神经支配的肌肉不同,因此这些变化似乎是运动单位自身转变的结果。这种现象被解释为神经运动系统维持对称性的一种代偿过程。

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本文引用的文献

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Pflugers Arch. 1981 Jun;390(3):246-9. doi: 10.1007/BF00658269.
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