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芬兰多发性硬化症的流行病学:高风险地区患病率上升及病灶稳定性

The epidemiology of multiple sclerosis in Finland: increase of prevalence and stability of foci in high-risk areas.

作者信息

Kinnunen E, Wikström J, Porras J, Palo J

出版信息

Acta Neurol Scand. 1983 May;67(5):255-62. doi: 10.1111/j.1600-0404.1983.tb04574.x.

DOI:10.1111/j.1600-0404.1983.tb04574.x
PMID:6880604
Abstract

Reliable data on the epidemiology of multiple sclerosis (MS) in Finland are available from 1964 and 1972. They show that the whole country is a high-risk area of MS with clustering in the western part. A reassessment of the prevalence data was carried out in the southern province of Uusimaa and in the western province of Vaasa, the prevalence day being January 1, 1979. The age-adjusted prevalence was 52.9 per 100,000 in Uusimaa and 92.9 per 100,000 in Vaasa, figures that were three times higher than those recorded for the same areas in 1964. The communities with the highest prevalence rates in the province of Vaasa were the same as those in the survey of 1972; some rates exceeded 200 per 100,000. The increase in the prevalence rates may be due to a better registration of MS cases, but it may also represent a true increase, a possibility that only can be answered by further incidence studies.

摘要

芬兰自1964年和1972年起便有关于多发性硬化症(MS)流行病学的确切数据。这些数据表明,芬兰全国都是MS的高风险地区,西部地区尤为集中。1979年1月1日,对芬兰南部的新地区以及西部的瓦萨省进行了患病率数据的重新评估。新地区年龄调整后的患病率为每10万人中有52.9人,瓦萨省为每10万人中有92.9人,这一数字比1964年同一地区记录的数字高出三倍。瓦萨省患病率最高的社区与1972年调查中的社区相同;一些患病率超过了每10万人中有200人。患病率的增加可能是由于MS病例登记情况有所改善,但也可能代表着实际增加,这一可能性只有通过进一步的发病率研究才能解答。

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