芬兰多发性硬化症患病率不断上升。

Increasing prevalence of multiple sclerosis in Finland.

作者信息

Sumelahti M L, Tienari P J, Wikström J, Palo J, Hakama M

机构信息

School of Public Health, University of Tampere and Department of Clinical Neurophysiology, Tampere University Hospital, Finland.

出版信息

Acta Neurol Scand. 2001 Mar;103(3):153-8. doi: 10.1034/j.1600-0404.2001.103003153.x.

DOI:10.1034/j.1600-0404.2001.103003153.x

PMID:11240562

Abstract

OBJECTIVES

To follow-up the prevalence trends of MS from 1983 to 1993 in western and southern Finland. MS epidemiology has been previously followed from 1964 to 1978 in these regions. The updated prevalences were correlated with incidence trends in the same period.

METHODS

Age-adjusted and age-specific MS prevalence rates were calculated for cases classified by Poser's criteria.

RESULTS

In the western health-care districts, Seinäjoki and Vaasa, prevalences in 1993 were 202/10(5) and 111/10(5). In the southern district Uusimaa the respective figure was 108/10(5). In Seinäjoki a significant 1.7-fold increase was found in 1993 as compared to 1983, mainly due to increased incidence. In Uusimaa a significant 1.2-fold increase in prevalence was found in the presence of stable incidence. In Vaasa prevalence was stable, although incidence was declining.

CONCLUSION

The prevalence of MS is increasing in Seinäjoki and Uusimaa but not in Vaasa. Both the prevalence and incidence in Seinäjoki are now among the highest reported.

摘要

目的

追踪1983年至1993年芬兰西部和南部多发性硬化症（MS）的患病率趋势。此前已对这些地区1964年至1978年的MS流行病学情况进行过追踪。将更新后的患病率与同期的发病率趋势进行关联分析。

方法

根据波泽尔（Poser）标准对病例进行分类，计算年龄调整后的和特定年龄组的MS患病率。

结果

在西部医疗保健区的塞纳约基（Seinäjoki）和瓦萨（Vaasa），1993年的患病率分别为202/10⁵和111/10⁵。在南部的新地区（Uusimaa），相应数字为108/10⁵。在塞纳约基，与1983年相比，1993年患病率显著增加了1.7倍，主要是由于发病率上升。在新地区，尽管发病率稳定，但患病率仍显著增加了1.2倍。在瓦萨，患病率稳定，尽管发病率在下降。