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前列腺素A2处理后松鼠肾上腺和肾脏中脂质的研究。

A study on lipids in the adrenal and kidney of squirrel after prostaglandin A2 treatment.

作者信息

Rana S V, Gupta V K

出版信息

Acta Morphol Neerl Scand. 1983 May;21(2):101-6.

PMID:6880864
Abstract

Prostaglandins have been assigned both physiological and pharmacological properties. Moreover, they have been identified in the renal tissue. Nevertheless, effects of exogenous prostaglandins on different systems are not fully known. Since PGA2 escapes destruction in the lungs, it functions as circulatory hormone. How prostaglandins of A group effect lipid metabolism in renal and adrenal tissues has been studied during this investigation. Qualitative and quantitative studies thus performed showed that PGA2 stimulated lipid activities in both the tissues. Whether they inhibited the transport of lipids away from these tissues or enhanced their biosynthesis is not known at present. However, histochemical studies on neutral lipids and phospholipids show that PGA2 stimulates lipid synthesis in these two issues.

摘要

前列腺素已被赋予生理和药理特性。此外,它们已在肾组织中被鉴定出来。然而,外源性前列腺素对不同系统的影响尚未完全清楚。由于PGA2在肺中不易被破坏,它起着循环激素的作用。在本次研究中,已对A组前列腺素如何影响肾和肾上腺组织中的脂质代谢进行了研究。如此进行的定性和定量研究表明,PGA2刺激了这两种组织中的脂质活性。目前尚不清楚它们是抑制脂质从这些组织中转运出去还是增强其生物合成。然而,对中性脂质和磷脂的组织化学研究表明,PGA2刺激了这两个组织中的脂质合成。

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