A study on lipids in the adrenal and kidney of squirrel after prostaglandin A2 treatment.

Prostaglandins have been assigned both physiological and pharmacological properties. Moreover, they have been identified in the renal tissue. Nevertheless, effects of exogenous prostaglandins on different systems are not fully known. Since PGA2 escapes destruction in the lungs, it functions as circulatory hormone. How prostaglandins of A group effect lipid metabolism in renal and adrenal tissues has been studied during this investigation. Qualitative and quantitative studies thus performed showed that PGA2 stimulated lipid activities in both the tissues. Whether they inhibited the transport of lipids away from these tissues or enhanced their biosynthesis is not known at present. However, histochemical studies on neutral lipids and phospholipids show that PGA2 stimulates lipid synthesis in these two issues.