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持续性非卧床腹膜透析患者的深红酵母腹膜炎

Rhodotorula rubra peritonitis in patients undergoing continuous ambulatory peritoneal dialysis.

作者信息

Eisenberg E S, Alpert B E, Weiss R A, Mittman N, Soeiro R

出版信息

Am J Med. 1983 Aug;75(2):349-52. doi: 10.1016/0002-9343(83)91216-0.

Abstract

Although still uncommon, fungal peritonitis is being reported with increasing frequency in patients with renal failure who are undergoing long-term peritoneal dialysis. Although most cases have involved Candida albicans, other opportunistic pathogens have been reported as well. Recently, three patients were seen with serious peritoneal infections due to Rhodotorula rubra, a "nonpathogenic" fungus. In two patients, peritoneal fibrosis made further peritoneal dialysis impossible. The third patient died from complications of peritonitis. Environmental cultures revealed a possible common-source outbreak. Literature review reveals that infection due to this organism is most unusual and occurs only in the hospital setting in patients with serious compromise of host defenses.

摘要

尽管真菌性腹膜炎仍不常见,但在接受长期腹膜透析的肾衰竭患者中,其报告频率正在增加。虽然大多数病例涉及白色念珠菌,但也有其他机会性病原体的报告。最近,有三名患者因深红酵母这种“非致病性”真菌导致严重的腹膜感染。在两名患者中,腹膜纤维化使进一步的腹膜透析无法进行。第三名患者死于腹膜炎并发症。环境培养显示可能存在共同来源的暴发。文献综述表明,这种生物体引起的感染非常罕见,仅发生在宿主防御严重受损的医院环境中的患者身上。

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