Blakeslee D, Raymond M J, Ward T, Bandy P
Cancer Lett. 1978 Jul;5(1):49-54. doi: 10.1016/s0304-3835(78)80010-x.
A small molecular weight factor with potent toxohormone activity was recovered from the serum-free culture supernatant of mouse MBQA fibrosarcoma cells. The factor depressed plasma-bound iron levels in mice and inhibited cell-free protein synthesis in microgram doses. Preliminary characterizations suggest that the active material is a small peptide.
从小鼠MBQA纤维肉瘤细胞的无血清培养上清液中分离出一种具有强毒素激素活性的小分子重量因子。该因子可降低小鼠血浆结合铁水平，并在微克剂量下抑制无细胞蛋白质合成。初步鉴定表明，活性物质是一种小肽。
