Johnson R G, Rosenkrantz K R, Preston R A, Hopkins C, Daggett W M
Ann Thorac Surg. 1983 Aug;36(2):173-9. doi: 10.1016/s0003-4975(10)60452-3.
The efficacy of postoperative autotransfusion in lowering the requirement for banked-blood transfusion was studied in two groups, each having 168 patients, who underwent cardiac operations between April, 1979, and May, 1980. A Sorenson autotransfusion system was available for use in the autotransfusion group, whereas the control group received routine closed mediastinal drainage. Of the autotransfusion group, 81% met the criterion for autotransfusion (mediastinal losses of 450 ml or more during 4 hours), but only 61% of the autotransfusion group actually received autologous blood (mean autotransfusion volume, 399 +/- 25 ml). The patients receiving autologous blood required significantly less banked blood than their matched controls (447 +/- 60 ml and 744 +/- 83 ml, respectively; p less than 0.001). In the subgroup of patients with large mediastinal losses (more than 1,250 ml), this difference was even greater (autotransfusion, 642 ml compared with control, 1,145 ml; p less than 0.01). Postoperative autotransfusion is a simple, safe, and cost-effective method to reduce dependence on banked blood, especially when mediastinal losses are large. Obtaining maximum benefit requires familiarity of staff with the system and use of a consistent protocol.
1979年4月至1980年5月期间，对两组各168例接受心脏手术的患者进行了研究，以探讨术后自体输血在降低库存血输血需求方面的疗效。自体输血组可使用索伦森自体输血系统，而对照组则接受常规的纵隔闭式引流。在自体输血组中，81%的患者符合自体输血标准（4小时内纵隔失血量达450毫升或更多），但实际上只有61%的自体输血组患者接受了自体血（自体输血平均量为399±25毫升）。接受自体血的患者所需的库存血明显少于匹配的对照组（分别为447±60毫升和744±83毫升；p<0.001）。在纵隔失血量较大（超过1250毫升）的患者亚组中，这种差异更大（自体输血组为642毫升，对照组为1145毫升；p<0.01）。术后自体输血是一种简单、安全且具有成本效益的方法，可减少对库存血的依赖，尤其是在纵隔失血量较大时。要获得最大益处，工作人员需要熟悉该系统并采用一致的方案。
