阿耳忒辛及其成分的致敏潜力评估。

Assessment of the allergenic potential of althesin and its constituents.

作者信息

Tachon P, Descotes J, Laschi-Loquerie A, Guillot J P, Evreux J C

出版信息

Br J Anaesth. 1983 Aug;55(8):715-7. doi: 10.1093/bja/55.8.715.

DOI:10.1093/bja/55.8.715

Abstract

The pharmaceutical formulation of Althesin was shown to have a weak allergenic potential in the guinea pig maximization test. Alphadolone and alphaxalone acetate were found to be devoid of such potential, while the status of Cremophor EL remained equivocal.

摘要

在豚鼠最大化试验中，阿尔忒辛的药物制剂显示出较弱的致敏潜力。发现α-羟孕二酮和醋酸α-羟孕二酮没有这种潜力，而聚氧乙烯蓖麻油EL的情况仍不明确。