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患有弗氏白血病的小鼠肝脏中的造血干细胞。

Hemopoietic stem cells in the liver of mice with Friend leukemia.

作者信息

Seidel H J, Kreja L

出版信息

Blut. 1983 Sep;47(3):139-45. doi: 10.1007/BF00320175.

DOI:10.1007/BF00320175
PMID:6882929
Abstract

Hemopoietic stem cells were studied in the marrow, spleen and liver of individual, FV-P infected DBA/2 mice. At more than 17 days after infection there was a tendency for CFU-EI numbers in the spleen to be reduced compared to earlier intervals after virus infection; CFU-EI numbers in the marrow were low. At the same time all hemopoietic stem cells (CFU-S, CFU-C, BFU-E and CFU-EI) could be found in the enlarged liver. The migration of stem cells from the marrow to the spleen and further to the liver is discussed.

摘要

对感染FV-P的DBA/2品系小鼠个体的骨髓、脾脏和肝脏中的造血干细胞进行了研究。感染后超过17天时，与病毒感染后的早期时间段相比，脾脏中的红细胞爆式形成单位-红细胞生成素（CFU-EI）数量有减少的趋势；骨髓中的CFU-EI数量较低。与此同时，在肿大的肝脏中可发现所有造血干细胞（脾集落形成单位、粒系集落形成单位、爆式红系集落形成单位和CFU-EI）。讨论了干细胞从骨髓迁移至脾脏并进一步迁移至肝脏的过程。

相似文献

1
Hemopoietic stem cells in the liver of mice with Friend leukemia.患有弗氏白血病的小鼠肝脏中的造血干细胞。
Blut. 1983 Sep;47(3):139-45. doi: 10.1007/BF00320175.
2
Kinetics of erythroid precursors in mice infected with the anemic or the polycythemic strain of Friend leukemia virus.感染贫血型或红细胞增多型弗氏白血病病毒的小鼠中红系前体细胞的动力学
Proc Natl Acad Sci U S A. 1980 Apr;77(4):2054-8. doi: 10.1073/pnas.77.4.2054.
3
Effects of tilorone on hemopoietic stem cells and on the development of Friend leukemia.泰洛龙对造血干细胞及弗氏白血病发展的影响。
Cancer Chemother Pharmacol. 1980;5(1):49-54. doi: 10.1007/BF00578562.
4
Expression of Friend leukemia virus and spleen focus-forming virus-specific sequences in erythroid bursts and granulocyte-macrophage colonies from spleen and marrow of mice infected with Friend leukemia virus.感染弗氏白血病病毒的小鼠脾脏和骨髓中红系爆式集落及粒-巨噬细胞集落中弗氏白血病病毒和脾集落形成病毒特异性序列的表达
Cancer Res. 1983 Feb;43(2):598-603.
5
Effects of ribavirin on the development of the Friend leukemia.利巴韦林对弗氏白血病发展的影响。
J Cancer Res Clin Oncol. 1980;98(1):41-50. doi: 10.1007/BF00413175.
6
Erythropoietin-independent erythroid colony formation in vitro by hemopoietic cells of mice infected with friend virus.感染弗氏病毒的小鼠造血细胞在体外形成不依赖促红细胞生成素的红系集落
Int J Cancer. 1975 Mar 15;15(3):467-82. doi: 10.1002/ijc.2910150313.
7
Reconstitution of the W/Wv stem cell differentiation defect by infection with Rauscher leukemia virus.通过劳氏肉瘤病毒感染重建W/Wv干细胞分化缺陷。
J Natl Cancer Inst. 1985 Aug;75(2):361-8.
8
Erythroleukemia induction by Friend leukemia virus. A host gene locus controlling early anemia or polycythemia and the rate of proliferation of late erythroid cells.弗瑞德白血病病毒诱导的红白血病。一个控制早期贫血或红细胞增多症以及晚期红系细胞增殖速率的宿主基因位点。
J Exp Med. 1982 Aug 1;156(2):398-414. doi: 10.1084/jem.156.2.398.
9
Extended self-renewal capacity of pluripotent hemopoietic stem cells: association with persistent Friend spleen focus-forming virus.多能造血干细胞的延长自我更新能力：与持续性弗瑞德脾集落形成病毒的关联
Cell. 1982 Dec;31(3 Pt 2):731-8. doi: 10.1016/0092-8674(82)90327-0.
10
Reduced Competitive Repopulation Capacity of Multipotential Hematopoietic Stem Cells in the Bone Marrow of Friend Virus-infected Fv2-resistant Mice.感染Friend病毒的Fv2抗性小鼠骨髓中多能造血干细胞的竞争性再增殖能力降低
In Vivo. 2017 May-Jun;31(3):313-320. doi: 10.21873/invivo.11061.

本文引用的文献

1
Lodging of CFU(S) under various circumstances in bone marrow, spleen and liver.在各种情况下，集落形成单位（CFU）在骨髓、脾脏和肝脏中的定植情况。
Exp Hematol. 1980 Aug;8(7):860-6.
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A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.正常小鼠骨髓细胞辐射敏感性的直接测量。
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Pathogenesis of mouse leukemia caused by Friend virus.弗瑞德病毒引发的小鼠白血病的发病机制。
Cancer Res. 1959 Jan;19(1):52-8.
4
Complete replacement of serum in primary cultures of erythropoietin-dependent red cell precursors (CFU-E) by albumin, transferrin, iron, unsaturated fatty acid, lecithin and cholesterol.用白蛋白、转铁蛋白、铁、不饱和脂肪酸、卵磷脂和胆固醇完全替代促红细胞生成素依赖性红细胞前体（CFU-E）原代培养中的血清。
Exp Cell Res. 1980 Mar;126(1):121-6. doi: 10.1016/0014-4827(80)90476-0.
5
Hematopoietic stem cells in Friend murine leukemia virus infected mice undergoing chemotherapy: failure to eradicate Ep-independent erythropoiesis by BCNU.接受化疗的感染弗氏鼠白血病病毒的小鼠中的造血干细胞：卡氮芥未能根除不依赖促红细胞生成素的红细胞生成。
Exp Hematol. 1982 Feb;10(2):151-60.
6
Normal and Friend virus specific cell compartments in Friend leukemia characterized by their sensitivity to actinomycin D in vivo.以体内对放线菌素D的敏感性为特征的Friend白血病中正常和Friend病毒特异性细胞区室。
Blut. 1981 Nov;43(5):287-96. doi: 10.1007/BF00320952.
7
Kinetics of erythroid precursors in mice infected with the anemic or the polycythemic strain of Friend leukemia virus.感染贫血型或红细胞增多型弗氏白血病病毒的小鼠中红系前体细胞的动力学
Proc Natl Acad Sci U S A. 1980 Apr;77(4):2054-8. doi: 10.1073/pnas.77.4.2054.
8
Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture.通过培养中的宏观集落形成检测小鼠骨髓中的红系祖细胞。
Exp Hematol. 1975 Jan;3(1):32-43.
9
Radiation induced hemopoiesis in adult mouse liver.成年小鼠肝脏中的辐射诱导造血作用。
Exp Hematol. 1977 Mar;5(2):136-40.
10
Presence of target cells for Friend (FVP) in the liver and spleen of early postnatal mice.出生后早期小鼠肝脏和脾脏中存在弗瑞德（FVP）的靶细胞。
Proc Soc Exp Biol Med. 1977 Feb;154(2):295-8. doi: 10.3181/00379727-154-39657.