Forni L G, Packer J E, Slater T F, Willson R L
Chem Biol Interact. 1983 Jul 15;45(2):171-7. doi: 10.1016/0009-2797(83)90066-2.
The absolute rates of reaction of the trichloromethylperoxy radical, CCl3OO., derived from carbon tetrachloride and the halothane peroxy radical, CF3CHClOO., with oleic, linoleic, linolenic and arachidonic acids have been determined using the fast reaction technique of pulse radiolysis. In general, the rates of reaction of the radical derived from carbon tetrachloride are approximately five times greater than those for the halothane related radical. In both cases the rate constant increases with increasing unsaturation of the fatty acid in agreement with the known greater susceptibility of polyunsaturated fatty acids to peroxidative decomposition.
利用脉冲辐解的快速反应技术，已测定了由四氯化碳衍生的三氯甲基过氧自由基（CCl3OO.）以及由氟烷衍生的过氧自由基（CF3CHClOO.）与油酸、亚油酸、亚麻酸和花生四烯酸的绝对反应速率。一般来说，由四氯化碳衍生的自由基的反应速率大约是与氟烷相关的自由基的五倍。在这两种情况下，速率常数都随着脂肪酸不饱和度的增加而增大，这与已知的多不饱和脂肪酸对过氧化分解的更高敏感性相一致。
