Tatsuta M, Okuda S
Endoscopy. 1983 Jul;15(4):243-5. doi: 10.1055/s-2007-1021523.
The extent of, and age-related changes in, the acid-secreting area in patients with duodenal ulcer were compared with those in patients with gastric ulcer and healthy subjects. Studies were made by the endoscopic Congo red test developed in our clinic. The incidence of a large acid-secreting area was significantly higher in patients with duodenal ulcer than in normal subjects or patients with gastric ulcer. Although the incidence of a large acid-secreting area decreased with age in patients with gastric ulcer and in normal subjects, an extensive acid-secreting area was found in patients with duodenal ulcer, irrespective of age. In endoscopic follow-up studies, shrinkage of the acid-secreting area was observed in 18.8% of the healthy subjects and 31.9% of the patients with gastric ulcer, but in only 2.4% of the patients with duodenal ulcer.
将十二指肠溃疡患者的泌酸区域范围及其与年龄相关的变化，与胃溃疡患者和健康受试者进行了比较。研究采用了我们诊所研发的内镜刚果红试验。十二指肠溃疡患者中大面积泌酸区域的发生率显著高于正常受试者或胃溃疡患者。尽管胃溃疡患者和正常受试者中大面积泌酸区域的发生率随年龄增长而降低，但十二指肠溃疡患者无论年龄大小均存在广泛的泌酸区域。在内镜随访研究中，18.8%的健康受试者和31.9%的胃溃疡患者出现了泌酸区域缩小，但十二指肠溃疡患者中仅有2.4%出现这种情况。
