十二指肠球部溃疡与胰腺外分泌功能减退之间的关联。
Association between duodenal bulb ulceration and reduced exocrine pancreatic function.
作者信息
Schulze S, Thorsgaard Pedersen N, Jørgensen M J, Møllmann K M, Rune S J
出版信息
Gut. 1983 Sep;24(9):781-3. doi: 10.1136/gut.24.9.781.
Abstract
Seventy two patients admitted to a medical department with dyspepsia but without a previous diagnosis of peptic ulcer disease or chronic pancreatitis were studied consecutively. A pancreatic function test (Lundh meal test) and an upper endoscopy was made in all patients. There was no difference in age, sex ratio, occurrence of upper abdominal pain or chronic alcoholism between the groups of patients with reduced pancreatic function (20) and the group with normal function (52). Seven duodenal ulcers were found, two in patients with normal pancreatic function (2/52 = 3.8%; 95% conf lim: 0.5-13.2) and five in patients with reduced pancreatic function (5/20 = 25%; 95% conf lim: 8.7-49.1). This difference was statistically significant (p less than 0.01). Duodenitis occurred with equal frequency in the two groups.
摘要
连续研究了72名因消化不良入住内科但既往无消化性溃疡病或慢性胰腺炎诊断的患者。所有患者均进行了胰腺功能测试（伦德餐试验）和上消化道内镜检查。胰腺功能减退组（20例）和功能正常组（52例）在年龄、性别比例、上腹痛发生率或慢性酒精中毒方面无差异。发现7例十二指肠溃疡，胰腺功能正常的患者中有2例（2/52 = 3.8%；95%可信区间：0.5 - 13.2），胰腺功能减退的患者中有5例（5/20 = 25%；95%可信区间：8.7 - 49.1）。这种差异具有统计学意义（p小于0.01）。两组十二指肠炎症的发生率相同。
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