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子宫内膜的黏液性化生:超微结构和组织化学特征

Mucinous metaplasia of the endometrium: ultrastructural and histochemical characteristics.

作者信息

Demopoulos R I, Greco M A

出版信息

Int J Gynecol Pathol. 1983;1(4):383-90. doi: 10.1097/00004347-198301040-00008.

DOI:10.1097/00004347-198301040-00008
PMID:6885226
Abstract

The histologic, ultrastructural, and histochemical characteristics of a focus of mucinous metaplasia in the endometrium of a postmenopausal woman are described and compared with normal endocervical and endometrial epithelium. While, architecturally, the simple coiled metaplastic glands resembled endometrial glands, cytologically, they resembled endocervical cells in the ultrastructural appearance of the mucin, as well as in the histochemical-staining properties of the intracellular secretory product. The location of the focal area of metaplasia in the fundus, apparently isolated from endocervical mucosa, as well as its architectural resemblance to endometrium, indicates that it originates from endometrium rather than endocervix.

摘要

描述了一名绝经后女性子宫内膜黏液化生灶的组织学、超微结构和组织化学特征,并与正常宫颈和子宫内膜上皮进行了比较。在结构上,简单的卷曲化生腺体类似于子宫内膜腺体,但在细胞学上,它们在黏液的超微结构外观以及细胞内分泌产物的组织化学染色特性方面类似于宫颈细胞。化生灶位于子宫底部,显然与宫颈黏膜分离,并且在结构上与子宫内膜相似,这表明它起源于子宫内膜而非宫颈。

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Virchows Arch. 2018 Jun;472(6):907-917. doi: 10.1007/s00428-018-2314-4. Epub 2018 Feb 14.