Beumer J, Harrison R, Sanders B, Kurrasch M
Head Neck Surg. 1983 Jul-Aug;5(6):514-21. doi: 10.1002/hed.2890050611.
Studies were done with 120 patients submitting to preradiation dental extraction within the radiation treatment volume. Bone necroses developed at the extraction sites in 17 patients (14.1%). The risk of bone necrosis in these patients is primarily dependent upon the size of the radiation treatment volume, radiation dose to mandibular bone, and healing time for the extraction wounds. Of the 13 mandibular bone necroses occurring at preradiation extraction sites, only two have not responded favorably to conservative management. Our data indicates that a policy of selected tooth removal, before radiation treatment, will minimize the risk of osteoradionecrosis. Mandibular molars with advanced chronic periodontal bone loss, residing within the proposed radiation field should be considered for removal before commencement of radiation treatment.
对120例在放射治疗范围内接受放疗前拔牙的患者进行了研究。17例患者(14.1%)拔牙部位出现骨坏死。这些患者发生骨坏死的风险主要取决于放射治疗范围的大小、下颌骨的放射剂量以及拔牙创口的愈合时间。在放疗前拔牙部位发生的13例下颌骨坏死中,只有2例对保守治疗反应不佳。我们的数据表明,在放疗前选择性拔牙的策略将使放射性骨坏死的风险降至最低。对于位于拟放疗区域内、患有晚期慢性牙周骨丧失的下颌磨牙,应在放疗开始前考虑拔除。