Babson S G, Clarke N G
J Pediatr. 1983 Sep;103(3):391-3. doi: 10.1016/s0022-3476(83)80409-0.
The high incidence of sudden infant death syndrome in infants born to teenage mothers prompted us to search for epidemiologic clues that might relate to SIDS causation. The death rate for SIDS was compared with that of other major causes of infant mortality in two maternal age groups (younger than 20 years and 30 to 34 years). In the neonatal period, a significantly greater overall mortality occurred in infants born to the younger mothers. This difference was primarily related to an excess of low-birth-weight infants dying from diseases of early infancy. "Weight-specific" mortality, however, was similar for the two groups. In the postneonatal period, when most SIDS occurs, the incidence was 5.2 per 1000 among infants of teenage mothers, compared with 1.0 in infants of the older mothers. A similar maternal-age-related incidence was observed for death from infections, accidents, and "other causes." By contrast, death from congenital anomalies was unrelated to maternal age in both periods. We conclude that many postneonatal deaths are influenced by environmental factors, including the age and maturity of the mother.
青少年母亲所生婴儿中婴儿猝死综合征的高发病率促使我们寻找可能与婴儿猝死综合征病因相关的流行病学线索。我们将婴儿猝死综合征的死亡率与两个母亲年龄组（20岁以下和30至34岁）中其他主要婴儿死亡原因的死亡率进行了比较。在新生儿期，年轻母亲所生婴儿的总体死亡率显著更高。这种差异主要与过多的低体重婴儿死于婴儿早期疾病有关。然而，两组的“体重特异性”死亡率相似。在婴儿猝死综合征最常发生的新生儿后期，青少年母亲所生婴儿的发病率为每1000例中有5.2例，而年龄较大母亲所生婴儿的发病率为每1000例中有1.0例。感染、意外事故和“其他原因”导致的死亡也观察到了类似的与母亲年龄相关的发病率。相比之下，先天性异常导致的死亡在两个时期均与母亲年龄无关。我们得出结论，许多新生儿后期死亡受环境因素影响，包括母亲的年龄和成熟度。
