Perlman J M, Volpe J J
Pediatrics. 1983 Sep;72(3):329-34.
The relationship of suctioning to changes in the cerebral circulation was studied in 35 premature newborn infants. The objectives of the study were to determine whether important alterations occur in cerebral hemodynamics with suctioning and whether such alterations relate to systemic hemodynamic events. A transcutaneous Doppler technique was used to measure blood flow velocity in the anterior cerebral arteries. A prominent increase in cerebral blood flow velocity was documented in nearly all patients. Accompanying the increase in cerebral flow velocity was a marked increase in blood pressure; thus, the increased cerebral flow velocity appeared to reflect directly changes in systemic hemodynamic events. Also accompanying the increase in cerebral flow velocity was a marked increase in intracranial pressure. These data suggest potentially deleterious effects of suctioning in the preterm infant at risk for the occurrence of intraventricular hemorrhage and raise questions regarding the advisability of routine suctioning of such infants.
对35例早产新生儿进行了研究,以探讨吸痰与脑循环变化之间的关系。该研究的目的是确定吸痰时脑血流动力学是否会发生重要改变,以及这些改变是否与全身血流动力学事件相关。采用经皮多普勒技术测量大脑前动脉的血流速度。几乎所有患者的脑血流速度均显著增加。伴随脑血流速度增加的是血压显著升高;因此,脑血流速度增加似乎直接反映了全身血流动力学事件的变化。伴随脑血流速度增加的还有颅内压显著升高。这些数据提示,吸痰对有发生脑室内出血风险的早产儿可能具有有害影响,并引发了关于对此类婴儿进行常规吸痰是否明智的疑问。