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多次给药后人体对苄达赖氨酸盐的口服吸收情况。

Oral absorption of bendazac lysine salt in man after repeated administrations.

作者信息

Barillari G, Iorio E, Galli Angeli D, Catanese B

出版信息

Pharmacol Res Commun. 1983 May;15(5):461-71. doi: 10.1016/s0031-6989(83)80066-6.

Abstract

The plasma levels of the lysine salt of bendazac were studied in man after repeated administrations. The substance was administered in 500 mg tablets three times daily for 21 days. Concentrations of bendazac ranging between 15 and 30 micrograms/ml were found in the plasma within 10 hours after the first administration. No significant differences were observed between the first and following days of treatment. Common laboratory and clinical tests did not show any marked change.

摘要

对人体多次服用苄达赖氨酸盐后的血浆水平进行了研究。该物质以500毫克片剂形式每日服用三次,共服用21天。首次给药后10小时内,血浆中苄达赖氨酸的浓度在15至30微克/毫升之间。治疗的第一天和后续几天之间未观察到显著差异。常规实验室检查和临床检查未显示任何明显变化。

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