Deknudt G, Léonard A
Environ Physiol Biochem. 1975;5(5):319-27.
Chromosome analysis has been performed on workers from a cadmium plant who were exposed to fumes and dust of cadmium and lead. The 35 workers were classified, according to the type and duration of exposure, into a group (cadmium service) exposed to high levels of lead and cadmium in the absence of zinc (23 people) and a group of rolling-mill workers subjected mostly to zinc but also to lower levels of lead and cadmium (12 people). A higher yield of severe chromosome anomalies (chromatid exchange, disturbance of spiralization, chromosome translocation, ring and dicentric chromosomes) together with a total lower number of structural aberrations was observed in the cadmium workers when compared with the rolling-mill group.
对一家镉厂中接触镉和铅的烟雾及粉尘的工人进行了染色体分析。这35名工人根据接触类型和时长被分为两组，一组是在无锌环境下接触高浓度铅和镉的工人（镉作业组，23人），另一组是主要接触锌但也接触较低浓度铅和镉的轧钢厂工人（12人）。与轧钢厂组相比，镉作业组观察到严重染色体异常（染色单体交换、螺旋化紊乱、染色体易位、环状染色体和双着丝粒染色体）的发生率更高，同时结构畸变总数更低。
