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庆大霉素和利福平对实验性葡萄球菌 - 铜绿假单胞菌感染的治疗效果及其对免疫过程的影响

[Therapeutic effectiveness of gentamycin and rifampicin in experimental staphylococcal-Pseudomonas aeruginosa infection and their effect on immunological processes].

作者信息

Dnestranskaia L I, Tsyganenko A Ia

出版信息

Antibiotiki. 1982 Aug;27(8):626-31.

PMID:6889836
Abstract

The survival level of the experimental animals with infection caused by Staphylococcus and Ps. aeruginosa was the highest when the animals were treated with a combination of gentamicin and rifampicin as compared to the use of every antibiotic alone. The combination had a more favourable effect on the plasmocytic reaction and production of the antibody-forming cells in the lymphoid organs which correlated with the therapeutic efficacy of the antibiotics.

摘要

与单独使用每种抗生素相比,当用庆大霉素和利福平联合治疗时,感染葡萄球菌和铜绿假单胞菌的实验动物的存活率最高。该联合用药对淋巴器官中的浆细胞反应和抗体形成细胞的产生有更有利的影响,这与抗生素的治疗效果相关。

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