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[利福平在实验性感染中的化疗效果]

[Chemotherapeutic effectiveness of rifampicin in experimental infections].

作者信息

Samoĭlova L N, Bodunkova L E, Berezina E K, Fomina I P

出版信息

Antibiotiki. 1976 Sep;21(9):828-32.

PMID:793516
Abstract

Studies on the chemotherapeutic action of rifampicin in treatment of staphylococcal sepsis and sepsis caused by gramnegative organisms showed its high efficacy only in treatment of the staphylococcal infection. By the level of its efficacy rifampicin was much superior to benzylpenicillin and especially tetracycline. No difference in the activity level of the antibiotic in treatment of staphylococcal infections caused by sensitive and multiple resistant staphylococcal strains was found. In treatment of the infections caused by gramnegative organisms the drug activity was moderate.

摘要

关于利福平治疗葡萄球菌败血症及革兰氏阴性菌所致败血症的化疗作用研究表明,其仅在治疗葡萄球菌感染方面具有高效性。就疗效水平而言,利福平远优于苄青霉素,尤其优于四环素。在治疗由敏感及多重耐药葡萄球菌菌株引起的葡萄球菌感染时,未发现该抗生素的活性水平存在差异。在治疗革兰氏阴性菌所致感染时,该药活性中等。

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1
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