McCarty M F
Med Hypotheses. 1982 Sep;9(3):283-91. doi: 10.1016/0306-9877(82)90157-8.
PGE1 appears to act as a physiological regulator of uteroplacental blood flow. Its vasodilatory, anti-vasopressor, and platelet stabilizing effects could be expected to counteract the placental ischemia, hypertension and excessive coagulation that are seen in pre-eclampsia. Supplementation with efficient essential fatty acid precursors of PGE1 reduces platelet aggregation, has been used with success in the treatment of hypertension and arterial vasospasm, and might offer a nutritional means of reducing the incidence and severity of pre-eclampsia. Assurance of adequate general nutrition also appears to be of importance in this regard.
前列腺素E1似乎起着子宫胎盘血流生理调节因子的作用。可以预期其血管舒张、抗血管升压及血小板稳定作用能够抵消子痫前期所见的胎盘缺血、高血压及过度凝血。补充高效的前列腺素E1必需脂肪酸前体可降低血小板聚集，已成功用于治疗高血压和动脉血管痉挛，并且可能提供一种减少子痫前期发病率和严重程度的营养方法。在这方面，确保充足的全面营养似乎也很重要。
