Mattes P, Peros G, Belohlavek D, Malfertheiner P, Herfarth C
Z Gastroenterol. 1980 Jun;18(6):325-7.
In polytraumatised or septic patients without adequate medical prophylaxis the incidence-rate of postoperative complications is very high. The incidence-rate of acute mucosal stress lesions is to be expected 100 per cent. The parenteral application of pirenzepine shows in comparison to placebo a clear protective effect measured as incidence-rate of stress lesion (p greater than 0,05) and occurrence of bleeding (p greater than 0,01).
在没有充分医学预防措施的多发伤或脓毒症患者中，术后并发症的发生率非常高。急性黏膜应激性病变的发生率预计为100%。与安慰剂相比，静脉注射哌仑西平在应激性病变发生率（p>0.05）和出血发生率（p>0.01）方面显示出明显的保护作用。
