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[给予盐酸 DL-肉碱后母鼠和胎鼠肺组织中纤溶酶原激活剂和纤溶酶抑制剂的检测(作者译)]

[Examination of plasminogen-activators and plasmin-inhibitors in maternal and fetal rat-lung-tissue after administration of DL-carnitine-hydrochloride (author's transl)].

作者信息

Hückmann T, Blasini R, Haas S, Krieglsteiner P, Erhardt W, Wriedt-Lübbe I, Blümel G

出版信息

Z Geburtshilfe Perinatol. 1980 Feb;184(1):54-9.

PMID:6894511
Abstract

In the formation and resolution of fibrinous pulmonary hyaline membranes of the type occurring in perinatal respiratory distress, the plasminogen activators and plasmin inhibitors contained in the tissue assume central importance. Carnitine does not change plasminogen activator activity and reduces the plasmin inhibitor content in the foetal rat lung. Hence, no inhibiting action on local fibrinolytic processes can be established for carnitine.

摘要

在围产期呼吸窘迫中出现的那种纤维蛋白性肺透明膜的形成和消退过程中,组织中所含的纤溶酶原激活剂和纤溶酶抑制剂起着核心作用。肉碱不会改变纤溶酶原激活剂的活性,却能降低胎鼠肺中的纤溶酶抑制剂含量。因此,无法确定肉碱对局部纤维蛋白溶解过程有抑制作用。

相似文献

1
[Examination of plasminogen-activators and plasmin-inhibitors in maternal and fetal rat-lung-tissue after administration of DL-carnitine-hydrochloride (author's transl)].[给予盐酸 DL-肉碱后母鼠和胎鼠肺组织中纤溶酶原激活剂和纤溶酶抑制剂的检测(作者译)]
Z Geburtshilfe Perinatol. 1980 Feb;184(1):54-9.
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Effect of carnitine on foetal rat lung dipalmitoyl phosphatidylcholine content and lung morphology. Carnitine and lung surfactant, I.肉碱对胎鼠肺二棕榈酰磷脂酰胆碱含量及肺形态的影响。肉碱与肺表面活性物质,I。
J Clin Chem Clin Biochem. 1990 May;28(5):313-8.
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Plasminogen activators and urokinase inhibitors in the lungs of foetuses and newborns.
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[Pharmacologic influencing of fetal phospholipide synthesis. Part II: Carnitin - a new way of dyspnea syndrome prophylaxis? (author's transl)].[胎儿磷脂合成的药理学影响。第二部分:肉碱——预防呼吸窘迫综合征的新方法?(作者译)]
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Arch Gynecol. 1979 Jul 20;228(1-4):204-5.
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[In vivo and in vitro investigations of the effect of decortilen (16-methylenprednisolone) on lecithin synthesis in the fetal lung (author's transl)].[去皮质素(16-亚甲基泼尼松龙)对胎儿肺卵磷脂合成影响的体内及体外研究(作者译)]
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