胆道闭锁：我们目前的进展如何？
Biliary atresia: Where do we stand now?
作者信息
Govindarajan Krishna Kumar
机构信息
Krishna Kumar Govindarajan, Department of Pediatric Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry 605006, India.
出版信息
World J Hepatol. 2016 Dec 28;8(36):1593-1601. doi: 10.4254/wjh.v8.i36.1593.
Abstract
The pathway from clinical suspicion to establishing the diagnosis of biliary atresia in a child with jaundice is a daunting task. However, investigations available help to point towards the correct diagnosis in reasonable time frame. Imaging by Sonography has identified several parameters which can be of utility in the diagnostic work up. Comparison of Sonography with imaging by Nuclear medicine can bring out the significant differences and also help in appropriate imaging. The battery of Biochemical tests, available currently, enable better understanding of the line-up of investigations in a given child with neonatal cholestasis. Management protocols enable standardized care with optimal outcome. The place of surgical management in biliary atresia is undisputed, although Kasai procedure and primary liver transplantation have been pitted against each other. This article functions as a platform to bring forth the various dimensions of biliary atresia.
摘要
对于一名黄疸患儿，从临床怀疑到确诊胆道闭锁的过程是一项艰巨的任务。然而，现有的检查有助于在合理的时间内指向正确的诊断。超声成像已经确定了几个在诊断评估中有用的参数。将超声检查与核医学成像进行比较，可以发现显著差异，也有助于进行适当的成像。目前可用的一系列生化检查，能够更好地理解特定新生儿胆汁淤积患儿的检查项目。管理方案能够实现标准化护理并取得最佳结果。尽管肝门空肠吻合术和原位肝移植一直存在争议，但手术治疗在胆道闭锁中的地位是无可争议的。本文作为一个平台，展示了胆道闭锁的各个方面。
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