二棕榈酰磷脂酰胆碱相变时的体积磁化率变化
Change in volume magnetic susceptibility at the phase transition of dipalmitoylphosphatidylcholine.
作者信息
Kunze R K, Ho J T, Day E P
出版信息
Biophys J. 1980 May;30(2):359-64. doi: 10.1016/S0006-3495(80)85100-9.
Abstract
We have observed a change at 41 degrees C in the relative volume magnetic susceptibility of an aqueous dispersion containing 13 wt% multilamellar dipalmitoylphosphatidylcholine (DPPC) vesicles. The magnitude of the change is consistent with the known density change of the phospholipid bilayer and the assumption that the mass susceptibility of the system is constant through the transition. The superconducting susceptometer used in this study of the sharp transition of DPPC will be able to detect 1% changes in bilayer density for 10 wt% dispersions even when the transition temperature and transition width of phospholipid vesicle under various experimental conditions.
摘要
我们观察到，在含有13 wt%多层二棕榈酰磷脂酰胆碱（DPPC）囊泡的水分散体中，相对体积磁化率在41摄氏度时发生了变化。变化的幅度与磷脂双层已知的密度变化以及系统的质量磁化率在转变过程中保持恒定的假设一致。本研究中用于DPPC急剧转变研究的超导磁化率计，即使在各种实验条件下磷脂囊泡的转变温度和转变宽度不同时，也能够检测出10 wt%分散体中双层密度1%的变化。
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本文引用的文献
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