小单层二棕榈酰磷脂酰胆碱囊泡稳定性的光子相关光谱研究
Photon correlation spectroscopy study on the stability of small unilamellar DPPC vesicles.
作者信息
Chang E L, Gaber B P, Sheridan J P
出版信息
Biophys J. 1982 Aug;39(2):197-201. doi: 10.1016/S0006-3495(82)84508-6.
Abstract
The growth in size of dipalmitoylphosphatidylcholine small unilamellar vesicles (SUV) below Tm has been studied by photon correlation spectroscopy and differential scanning calorimetry. We see an initial fast rise of the hydrodynamic diameter of the vesicles followed by a slower increase. We assign the slow component of the size change to fusion of SUV. The order of the kinetics appears to be higher than first order. The estimated half lifetime of the fusion is approximately 67 h. The diameters for the fast and slow processes at t = O are 756 and 256 A, respectively, while as t leads to infinity the diameters increase to 1,570 and 733 A, respectively.
摘要
通过光子相关光谱法和差示扫描量热法研究了低于熔点温度（Tm）时二棕榈酰磷脂酰胆碱小单层囊泡（SUV）的尺寸增长情况。我们观察到囊泡的流体动力学直径最初快速增加，随后增长变缓。我们将尺寸变化的缓慢部分归因于SUV的融合。动力学级数似乎高于一级。估计融合的半衰期约为67小时。在t = 0时，快速和缓慢过程的直径分别为756 Å和256 Å，而当t趋于无穷大时，直径分别增加到1570 Å和733 Å。
相似文献
1
Photon correlation spectroscopy study on the stability of small unilamellar DPPC vesicles.小单层二棕榈酰磷脂酰胆碱囊泡稳定性的光子相关光谱研究
Biophys J. 1982 Aug;39(2):197-201. doi: 10.1016/S0006-3495(82)84508-6.
2
Thermodynamic characterization of the pretransition of unilamellar dipalmitoyl-phosphatidylcholine vesicles.单层二棕榈酰磷脂酰胆碱囊泡预转变的热力学表征。
Lipids. 1984 Jun;19(6):395-400. doi: 10.1007/BF02537400.
3
Effect of lamellarity and size on calorimetric phase transitions in single component phosphatidylcholine vesicles.片层结构和尺寸对单组分磷脂酰胆碱囊泡中热致相变的影响。
Biochim Biophys Acta. 2015 Feb;1848(2):532-43. doi: 10.1016/j.bbamem.2014.10.003. Epub 2014 Oct 22.
4
Effect of Gd3+ on the colloidal stability of liposomes.钆离子（Gd3+）对脂质体胶体稳定性的影响。
Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Sep;74(3 Pt 1):031913. doi: 10.1103/PhysRevE.74.031913. Epub 2006 Sep 25.
5
Aggregation of dipalmitoylphosphatidylcholine vesicles.二棕榈酰磷脂酰胆碱囊泡的聚集
Biochemistry. 1982 Aug 17;21(17):4133-9. doi: 10.1021/bi00260a033.
6
Kinetic studies of the interaction of fatty acids with phosphatidylcholine vesicles (liposomes).脂肪酸与磷脂酰胆碱囊泡（脂质体）相互作用的动力学研究。
Colloids Surf B Biointerfaces. 2006 Mar 1;48(1):24-34. doi: 10.1016/j.colsurfb.2006.01.001. Epub 2006 Feb 8.
7
Solubilisation of dipalmitoylphosphatidylcholine bilayers by sodium taurocholate: a model to study the stability of liposomes in the gastrointestinal tract and their mechanism of interaction with a model bile salt.牛磺胆酸钠对二棕榈酰磷脂酰胆碱双层膜的增溶作用：一种研究脂质体在胃肠道中的稳定性及其与模型胆盐相互作用机制的模型。
Eur J Pharm Biopharm. 2009 Feb;71(2):346-55. doi: 10.1016/j.ejpb.2008.09.004. Epub 2008 Sep 18.
8
Molecular interactions in imatinib-DPPC liposomes.伊马替尼 - 二棕榈酰磷脂酰胆碱脂质体中的分子相互作用。
Eur J Pharm Sci. 2006 Feb;27(2-3):205-11. doi: 10.1016/j.ejps.2005.09.011. Epub 2005 Nov 9.
9
Properties of mixed DOTAP-DPPC bilayer membranes as reported by differential scanning calorimetry and dynamic light scattering measurements.差示扫描量热法和动态光散射测量所报告的混合二油酰基三甲基氯化铵-二棕榈酰磷脂酰胆碱双层膜的性质。
J Phys Chem B. 2007 Aug 23;111(33):10032-9. doi: 10.1021/jp071722g. Epub 2007 Jul 31.
10
The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes.KLA 两亲性肽的螺旋倾向增强了它们与凝胶态脂质膜的结合。
Biophys Chem. 2013 Oct-Nov;180-181:10-21. doi: 10.1016/j.bpc.2013.05.003. Epub 2013 May 24.
引用本文的文献
1
Albumin-based nanoparticles as magnetic resonance contrast agents: I. Concept, first syntheses and characterisation.基于白蛋白的纳米颗粒作为磁共振对比剂：I. 概念、首次合成与表征。
Histochem Cell Biol. 2010 Apr;133(4):375-404. doi: 10.1007/s00418-010-0676-z. Epub 2010 Feb 20.
2
Structure of lipid tubules formed from a polymerizable lecithin.可聚合的磷脂形成的脂质小管的结构。
Biophys J. 1985 Dec;48(6):899-906. doi: 10.1016/S0006-3495(85)83852-2.
3
Selectivity of the anthracyclines for negatively charged model membranes: role of the amino group.蒽环类药物对带负电荷模型膜的选择性：氨基的作用。
Cancer Chemother Pharmacol. 1988;21(4):274-80. doi: 10.1007/BF00264191.
4
Probing the structure of diacetylenic phospholipid tubules with fluorescent lipophiles.用荧光亲脂性物质探究二乙炔基磷脂小管的结构。
Biophys J. 1990 May;57(5):925-33. doi: 10.1016/S0006-3495(90)82612-6.
本文引用的文献
1
Hydrostatic pressure in small phospholipid vesicles.小磷脂囊泡中的流体静压。
Proc Natl Acad Sci U S A. 1979 Jul;76(7):3318-9. doi: 10.1073/pnas.76.7.3318.
2
Kinetic and thermodynamic studies of the fusion of small unilamellar phospholipid vesicles.小单层磷脂囊泡融合的动力学和热力学研究
Biochim Biophys Acta. 1982 Feb 8;685(1):87-93. doi: 10.1016/0005-2736(82)90038-4.
3
Vesicle- vesicle interactions in sonicated dispersions of dipalmitoylphosphatidylcholine.二棕榈酰磷脂酰胆碱超声分散体中的囊泡-囊泡相互作用
Biochemistry. 1981 Aug 4;20(16):4792-7. doi: 10.1021/bi00519a041.
4
Fusion of dipalmitoylphosphatidylcholine vesicles.二棕榈酰磷脂酰胆碱囊泡的融合
Biochemistry. 1980 Aug 19;19(17):3919-23. doi: 10.1021/bi00558a005.
5
Studies on phosphatidylcholine vesicles. Formation and physical characteristics.磷脂酰胆碱囊泡的研究。形成与物理特性。
Biochemistry. 1969 Jan;8(1):344-52. doi: 10.1021/bi00829a048.
6
A calorimetric and fluorescent probe study of the gel-liquid crystalline phase transition in small, single-lamellar dipalmitoylphosphatidylcholine vesicles.小的单双层二棕榈酰磷脂酰胆碱囊泡中凝胶-液晶相变的量热和荧光探针研究。
Biochemistry. 1976 Apr 6;15(7):1393-401. doi: 10.1021/bi00652a007.
7
A light-scattering characterization of membrane vesicles.膜泡的光散射特性
Biophys J. 1976 Apr;16(4):337-56. doi: 10.1016/S0006-3495(76)85692-5.
8
Determination by photon correlation spectroscopy of particle size distributions in lipid vesicle suspensions.通过光子相关光谱法测定脂质囊泡悬浮液中的粒径分布。
Biophys J. 1977 Sep;19(3):265-73. doi: 10.1016/S0006-3495(77)85586-0.
9
Relaxation phenomena in aqueous dispersions of synthetic lecithins.合成卵磷脂水分散体中的弛豫现象。
Biochemistry. 1977 Jun 14;16(12):2674-80. doi: 10.1021/bi00631a014.
10
The effects of the thermal prephase transition and salts on the coagulation and flocculation of phosphatidylcholine bilayer vesicles.
Biochim Biophys Acta. 1978 May 4;509(1):111-28. doi: 10.1016/0005-2736(78)90012-3.
Zotero 插件