Halbert R E
Arch Pathol Lab Med. 1982 Oct;106(10):517-20.
A case of metastatic, poorly differentiated gastric adenocarcinoma in a 22-year-old woman with Peutz-Jeghers syndrome was studied. The young age of many patients who have gastrointestinal (GI) carcinoma associated with this syndrome, as well as the unusual locations of primary tumors (eg, duodenum), suggest an increased tendency toward malignant transformation in the upper Gl tract. Statistical support of this contention, however, is unavailable from presently available data.
