Wada K, Tanaka M, Yamaguchi K, Wada K
Dig Dis Sci. 1987 Aug;32(8):943-6. doi: 10.1007/BF01296719.
Peutz-Jeghers syndrome is a genetic condition characterized by mucocutaneous pigmentation and gastrointestinal polyposis. A variety of neoplasms have been found in the alimentary tract or elsewhere in patients with this entity. A 39-year-old female patient who had carcinoma and two polyps in the gallbladder in association with Peutz-Jeghers syndrome is described. Since the polyps consisted of the normal lining epithelium of the gallbladder and pseudopyloric gland-type metaplastic cells and obviously lacked cellular atypism, the authors would consider them hamartomatous. The carcinoma partly showing submucosal invasion existed in an area other than the polyps. This is the first documented case of the syndrome having gallbladder carcinoma.
佩-吉综合征是一种以皮肤黏膜色素沉着和胃肠道息肉病为特征的遗传性疾病。在患有该疾病的患者的消化道或其他部位发现了多种肿瘤。本文描述了一名39岁的女性患者，她患有佩-吉综合征，同时伴有胆囊癌和两个胆囊息肉。由于息肉由胆囊的正常内衬上皮和假幽门腺型化生细胞组成，且明显缺乏细胞异型性，作者认为它们是错构瘤性的。部分表现为黏膜下浸润的癌存在于息肉以外的区域。这是首例有文献记载的患有胆囊癌的该综合征病例。
