Graybill J R, Mitchell L
Infect Immun. 1978 Aug;21(2):674-7. doi: 10.1128/iai.21.2.674-677.1978.
BALB/c mice were given cyclophosphamide and challenged with Cryptococcus neoformans. Delayed-type hypersensitivity was transiently depressed, and survival was either unaffected or shortened by cyclophosphamide.
给BALB/c小鼠注射环磷酰胺,然后用新型隐球菌进行攻击。迟发型超敏反应暂时受到抑制,环磷酰胺对小鼠的存活率要么没有影响,要么使其缩短。