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环磷酰胺预处理与疟疾防护

Cyclophosphamide pretreatment and protection against malaria.

作者信息

Finerty J F, Krehl E P

出版信息

Infect Immun. 1976 Oct;14(4):1103-5. doi: 10.1128/iai.14.4.1103-1105.1976.

Abstract

Mice pretreated with cyclophosphamide were able to overcome infection from a lethal malarial strain. The development of resistance was preceded by increased hypersensitivity to malarial antigens. Hypersensitivity was demonstrable by a delayed footpad swelling technique.

摘要

用环磷酰胺预处理的小鼠能够抵御致死性疟原虫株的感染。在产生抗性之前,对疟原虫抗原的超敏反应增强。超敏反应可通过延迟足垫肿胀技术来证明。

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