Finerty J F, Krehl E P
Infect Immun. 1976 Oct;14(4):1103-5. doi: 10.1128/iai.14.4.1103-1105.1976.
Mice pretreated with cyclophosphamide were able to overcome infection from a lethal malarial strain. The development of resistance was preceded by increased hypersensitivity to malarial antigens. Hypersensitivity was demonstrable by a delayed footpad swelling technique.
用环磷酰胺预处理的小鼠能够抵御致死性疟原虫株的感染。在产生抗性之前,对疟原虫抗原的超敏反应增强。超敏反应可通过延迟足垫肿胀技术来证明。