Langford H G
Heart Lung. 1981 Mar-Apr;10(2):269-74.
Tribes that exist on a very low salt intake while consuming large amounts of potassium, and whose members are quite small and thin, develop practically no hypertension. Within the Western world little correlation between sodium intake and blood pressure can be found in the untreated patient. However, as individuals with high-normal blood pressure develop further blood pressure elevation on sodium loading, those with a family history of hypertension or high-normal blood pressure should restrict their sodium intake. There is a modest amount of evidence to suggest that potassium protects against the blood pressure-raising effects of sodium. The case for sodium restriction is best demonstrated in the treated hypertensive patient. Modest sodium restriction will enable the treated hypertensive patient to obtain good blood pressure control with much less drug intake and, therefore, less drug side effect.
一些部落的人盐摄入量极低，同时摄入大量钾，而且部落成员身材瘦小，几乎不会患高血压。在西方世界，未接受治疗的患者中钠摄入量与血压之间几乎没有关联。然而，血压略高于正常水平的个体在摄入钠后血压会进一步升高，因此有高血压家族病史或血压略高于正常水平的人应该限制钠的摄入量。有一定证据表明钾可以抵御钠的升压作用。限制钠摄入对已接受治疗的高血压患者最为有效。适度限制钠摄入能使接受治疗的高血压患者在减少药物摄入量的情况下实现良好的血压控制，从而减少药物副作用。
