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对新生儿重症监护病房中的新生儿进行耐药肠道杆菌监测和抗菌药物使用监测是否有用?

Are surveillance of resistant enteric bacilli and antimicrobial usage among neonates in a newborn intensive care unit useful?

作者信息

White R D, Townsend T R, Stephens M A, Moxon E R

出版信息

Pediatrics. 1981 Jul;68(1):1-4.

PMID:6909682
Abstract

From March 1976 through December 1978, the prevalence of ampicillin- and gentamicin-resistant enteric bacilli was monitored in fecal cultures of neonates in an intensive care unit. Substantial fluctuations in colonization rates were observed which did not correlate with the occurrence of sepsis due to these organisms nor with variations in antibiotic use. This experience suggests that the availability of these surveillance data did not result in more effective control of neonatal sepsis due to enteric bacilli.

摘要

从1976年3月至1978年12月,在一个重症监护病房对新生儿粪便培养物中氨苄西林和庆大霉素耐药性肠道杆菌的流行情况进行了监测。观察到定植率有很大波动,这些波动与这些微生物引起的败血症发生率以及抗生素使用的变化均无关联。这一经验表明,这些监测数据的可得性并未导致对肠道杆菌引起的新生儿败血症进行更有效的控制。

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引用本文的文献

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Molecular epidemiology of Enterobacter cloacae in a neonatal department: a 2-year surveillance study.新生儿科阴沟肠杆菌的分子流行病学:一项为期2年的监测研究。
Eur J Clin Microbiol Infect Dis. 2008 Aug;27(8):643-8. doi: 10.1007/s10096-008-0484-8. Epub 2008 Mar 5.
2
Antibiotic use in the neonatal unit.新生儿病房中的抗生素使用。
Arch Dis Child. 1987 Feb;62(2):204-8. doi: 10.1136/adc.62.2.204.
3
Factors influencing colonisation with gentamicin resistant gram negative organisms in the neonatal unit.新生儿重症监护病房中影响耐庆大霉素革兰氏阴性菌定植的因素
Arch Dis Child. 1988 May;63(5):533-5. doi: 10.1136/adc.63.5.533.
4
Neonatal pneumonia.新生儿肺炎
Arch Dis Child. 1990 Feb;65(2):207-11. doi: 10.1136/adc.65.2.207.