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在经干扰素处理的、被莫洛尼鼠白血病病毒有效感染的小鼠细胞中病毒特异性RNA的合成

Virus-specific RNA synthesis in interferon-treated mouse cells productively infected with Moloney murine leukemia virus.

作者信息

Fan H, MacIsaac P

出版信息

J Virol. 1978 Aug;27(2):449-52. doi: 10.1128/JVI.27.2.449-452.1978.

Abstract

Mouse cells productively infected with Moloney murine leukemia virus were treated with interferon, and intracellular virus-specific RNA was studied by hybridization with complementary DNA. The steady-state concentration of virus-specific RNA in interferon-treated cells was somewhat greater than that in untreated cells, and the rates of virus-specific RNA synthesis were approximately equal in treated and untreated cells.

摘要

用莫洛尼氏鼠白血病病毒有效感染的小鼠细胞用干扰素处理,并用互补DNA杂交研究细胞内病毒特异性RNA。干扰素处理细胞中病毒特异性RNA的稳态浓度略高于未处理细胞,且处理细胞和未处理细胞中病毒特异性RNA的合成速率大致相等。

相似文献

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Measurement of interferon effects on murine leukemia virus (MuLV)-infected cells.
Methods Enzymol. 1981;79(Pt B):422-32. doi: 10.1016/s0076-6879(81)79055-4.
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Quantification of newly synthesized virus RNA in moloney murine leukaemia virus-infected cells.
J Gen Virol. 1980 Jun;48(Pt 2):341-50. doi: 10.1099/0022-1317-48-2-341.

本文引用的文献

10
Antiviral activity of interferons.干扰素的抗病毒活性。
Bacteriol Rev. 1977 Sep;41(3):543-67. doi: 10.1128/br.41.3.543-567.1977.

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