补体因子Bf、C2和C6在西太平洋地区的分布情况。
Distribution of complement factors Bf, C2 and C6 in the Western Pacific.
作者信息
Ranford P R, Kirk R L, Zimmet P
出版信息
Acta Anthropogenet. 1982;6(1):23-32.
Complement components Bf, C2 and C6 have been typed in various Micronesian, Polynesian, Melanesian and Indian populations of the Western Pacific. BfS and BfF gene frequencies are heterogeneous throughout the region but the number of alleles in the Bf system is restricted. C2 is also restricted with the C22 gene frequency from 0-1.3% in all groups except Fijian Indians where it is 4.8%. The C6A and C6B frequencies of Polynesians, Melanesians and Fijian Indians are within the narrow range of frequencies reported for these alleles from other parts of the world. In the Micronesians of Nauru, a third polymorphic allele (C6Nauru) occurs together with a number of rare alleles (C6R). The Nauruan C6 gene frequencies are C6A 44.6%, C6B 45.2%, C6Nauru 6.7% and C6R 3.5% C6Nauri is present in low frequencies in most other Western Pacific populations and C6R variants occur in Polynesians.
补体成分Bf、C2和C6已在西太平洋的各种密克罗尼西亚、波利尼西亚、美拉尼西亚和印度人群中进行了分型。BfS和BfF基因频率在整个区域内是异质的，但Bf系统中的等位基因数量有限。C2也有限制，除斐济印度人（其频率为4.8%）外，所有群体中C22基因频率为0 - 1.3%。波利尼西亚人、美拉尼西亚人和斐济印度人的C6A和C6B频率处于世界其他地区报道的这些等位基因频率的狭窄范围内。在瑙鲁的密克罗尼西亚人中，第三个多态性等位基因（C6瑙鲁）与一些罕见等位基因（C6R）一起出现。瑙鲁人的C6基因频率为C6A 44.6%、C6B 45.2%、C6瑙鲁6.7%和C6R 3.5%。C6瑙鲁在大多数其他西太平洋人群中的频率较低，C6R变体出现在波利尼西亚人中。
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