Teng Y S, Tan S G
Hum Hered. 1982;32(5):362-6. doi: 10.1159/000153323.
Properdin factor B (Bf) is a polymorphic protein in the human plasma. Two common alleles, BfS, BfF, and two rare alleles, BfF1, BfS1, have been demonstrated in Caucasians. We now report that BfF can be subtyped into two alleles, BfFa and BfFb by isoelectrofocusing. Family studies indicate that they are inherited in a co-dominant pattern. Gene frequencies for Caucasians are: BfS 0.808, BfF1 0.019, BfS1 0.005, BfFa 0.038 and BfFb 0.128.
备解素因子B(Bf)是人类血浆中的一种多态性蛋白质。在白种人中已证实有两个常见等位基因BfS、BfF以及两个罕见等位基因BfF1、BfS1。我们现在报告,通过等电聚焦可将BfF进一步分为两个等位基因BfFa和BfFb。家系研究表明它们以共显性模式遗传。白种人的基因频率为:BfS 0.808、BfF1 0.019、BfS1 0.005、BfFa 0.038和BfFb 0.128。