Branchi M, Patriarca P L, Bordoni P
Pediatr Med Chir. 1982 Nov-Dec;4(6):635-8.
Measurements of serum calcium on the first, third and sixth day of life and serum Parathyroid hormone (PTH) and Calcitonin (CT) by radioimmunoassay on the first and third day of life have been effected on a group of 31 infants born after 29-42 weeks of gestation and weighing at birthday 1300-3510 g. The mean serum iCT levels on the first day of life (996 +/- 95 pg/ml) were significantly higher than on the third day of life (533 +/- 79 pg/ml; p less than 0,001) and both were upper normal range of method (200 pg/ml). Mean serum iCT values were found negatively correlated both with birthweight (p less than 0,025) and with gestational age (on 1st day p less than 0,02; on 3rd day p less than 0,001) in AGA newborns. No correlation was found between iCT values and serum Calcium values. The mean serum iPTH levels on the first and third day of life were in the normal range (on 1st day 416 +/- 61 pg/ml; on 3 rd day 640 +/- 114 pg/ml) and not correlated neither with serum Calcium and serum iCT levels, nor with birthweight and gestational age of the newborns. It is excluded that any transient hypoparathyroidism can cause early neonatal hypocalcemia and it is confirmed the presence of high levels of serum Calcitonin in term and premature infants.
对一组31名孕29 - 42周出生、出生体重1300 - 3510克的婴儿，在出生后第1天、第3天和第6天测量血清钙，并在出生后第1天和第3天通过放射免疫法测定血清甲状旁腺激素（PTH）和降钙素（CT）。出生后第1天血清iCT水平的平均值（996±95 pg/ml）显著高于出生后第3天（533±79 pg/ml；p<0.001），且两者均高于该方法的正常上限（200 pg/ml）。在适于胎龄（AGA）新生儿中，发现平均血清iCT值与出生体重（p<0.025）和胎龄均呈负相关（第1天p<0.02；第3天p<0.001）。未发现iCT值与血清钙值之间存在相关性。出生后第1天和第3天血清iPTH水平的平均值在正常范围内（第1天416±61 pg/ml；第3天|640±114 pg/ml），且与新生儿的血清钙和血清iCT水平、出生体重及胎龄均无相关性。排除了任何短暂性甲状旁腺功能减退可导致早期新生儿低钙血症的情况，并证实足月儿和早产儿血清降钙素水平较高。
