荷瘤人体肢体：一种离体模型。
The human tumor-bearing limb: an ex vivo model.
作者信息
Burt M E, Norton J A, Brennan M F
出版信息
Surgery. 1980 Feb;87(2):128-32.
The present report describes a viable, isolated, perfused, human, tumor-bearing limb model suitable for the study of human host-tumor metabolism. The model is hemodynamically stable with high flow rates (50 cc/kg/min) and low perfusion pressures (mean, 77.2 mm Hg) which are stable over time. Metabolically, the preparation is viable with initial oxygen and glucose uptake 0.88 cc/kg/min and 0.029 mmole/kg/min, respectively. These parameters and lactate concentrations do not change significantly with time.
本报告描述了一种适用于研究人类宿主 - 肿瘤代谢的可行、分离、灌注的荷瘤人肢体模型。该模型血流动力学稳定，具有高流速（50 cc/kg/min）和低灌注压力（平均77.2 mmHg），且这些参数随时间保持稳定。在代谢方面，该制剂是有活力的，初始氧摄取量和葡萄糖摄取量分别为0.88 cc/kg/min和0.029 mmole/kg/min。这些参数和乳酸浓度随时间无显著变化。
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