Dolles O K, Gjermo P
Scand J Dent Res. 1980 Feb;88(1):22-7. doi: 10.1111/j.1600-0722.1980.tb00715.x.
A total of 91 schoolchildren, 13 years of age, were distributed into three groups. Three test dentifrices were used containing 0.1% NaF, 0.1% NaF and 2% chlorhexidine, and 2% chlorhexidine, respectively. The caries increment and gingival conditions over a period of 2 years were recorded. The caries data of the groups were compared and related to two reference groups in order to estimate a possible influence upon the study results by a change in caries incidence general to the area and age groups in question. There was less caries in the group using the dentifrice containing fluoride and chlorhexidine than in the two other test groups. The differences in caries increment between the groups were not statistically significant. The gingival health seemed to improve in all groups, but there were no statistically significant differences between the groups. The caries data from the reference groups indicated that the general trend towards reduced caries incidence was different from that of the study group.
共有91名13岁的学童被分成三组。分别使用了三种测试牙膏,一种含0.1%氟化钠,一种含0.1%氟化钠和2%氯己定,还有一种含2%氯己定。记录了2年期间的龋齿增量和牙龈状况。将各实验组的龋齿数据与两个参照组进行比较,并考虑到所研究地区和年龄组龋齿发病率的变化对研究结果可能产生的影响。使用含氟和氯己定牙膏的组比其他两个测试组的龋齿更少。各实验组之间的龋齿增量差异无统计学意义。所有组的牙龈健康状况似乎都有所改善,但组间差异无统计学意义。参照组的龋齿数据表明,龋齿发病率总体下降趋势与实验组不同。