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Serum theophylline levels in adult asthmatics: comparison of oral sustained-release and microcrystalline preparations.

作者信息

Jones D T, Sears M R

出版信息

N Z Med J. 1980 Sep 10;92(667):196-8.

PMID:6933358
Abstract

Serial serum theophylline levels were measured in 20 inpatient asthmatics given tablets of either microcrystalline or sustained-release theophylline. The sustained-release preparation gave serum levels which were more consistently within the therapeutic range with a significantly higher trough concentration. No increase in adverse effects was encountered.

摘要

相似文献

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Serum theophylline levels in adult asthmatics: comparison of oral sustained-release and microcrystalline preparations.
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引用本文的文献

1
Disposition and clinical pharmacokinetics of theophylline after administration of a new sustained release tablet.一种新型缓释片给药后茶碱的处置及临床药代动力学
Eur J Clin Pharmacol. 1981;21(1):39-44. doi: 10.1007/BF00609586.
2
Bioavailability and diurnal variation in absorption of sustained release theophylline in asthmatic children.哮喘儿童中缓释型茶碱的生物利用度及吸收的昼夜变化
Eur J Clin Pharmacol. 1983;25(5):667-72. doi: 10.1007/BF00542356.
3
A clinical and pharmacokinetic basis for the selection and use of slow release theophylline products.
缓释型茶碱产品选用的临床及药代动力学依据
Clin Pharmacokinet. 1984 Mar-Apr;9(2):95-135. doi: 10.2165/00003088-198409020-00001.