Carl W, Wood R
J Am Dent Assoc. 1980 Oct;101(4):646-8. doi: 10.14219/jada.archive.1980.0368.
Underdevelopment of teeth after exposure to radiation has been observed since the early experiments with X rays. Two patients had been irradiated at young ages for embryonal rhabdomyosarcomas. For the patient treated with radiation at age 4 for a lesion in the submandibular area, root development of the mandibular teeth stopped, but the teeth nevertheless erupted. In the patient treated with radiation at age 9 for a tumor in the left cheek, bone apposition in the left side of the mandible failed to continue at the same rate as on the right side. Although new megavoltage radiation machines have reduced the chances of bone complications in adults, developing bone and structures are still significantly affected by radiation.
自早期X射线实验以来，人们就观察到辐射暴露后牙齿发育不全的情况。两名患者在幼年时因胚胎性横纹肌肉瘤接受了放射治疗。一名4岁时因下颌下区病变接受放射治疗的患者，下颌牙齿的牙根发育停止，但牙齿仍萌出。另一名9岁时因左侧脸颊肿瘤接受放射治疗的患者，下颌骨左侧的骨附着未能以与右侧相同的速度继续进行。尽管新的兆伏级放射治疗设备减少了成人发生骨并发症的几率，但正在发育的骨骼和结构仍会受到辐射的显著影响。
